Webmaster: MVG - Last update: June 2017

EQUIPMENT

 

Isothermal Titration Calorimetry:

Two nano-ITC systems from TA instruments, one ITC 4200 with 1.3 ml removable cells and a Nano-ITC 2G with 1 ml non-removable cells.  These systems are ideal for the characterization of intermolecular interactions, from small organic molecules to biological macromolecules, and can be used both with aqueous or organic solutions.

 

Differential Scanning Calorimetry:

A nano-DSC III from TA instruments with a 300 μl capillary cell specifically designed to determine the thermal stability and heat capacity of proteins and other macromolecules or macromolecular assemblies (liposomes) in dilute solution.

 

UV-Vis-NIR Absorption Spectrophotometer:

Equipped with a Pelletier Temperature Controller and an Integration Sphere allowing the characterization of low volume liquid samples (150 μl) and solid samples from 200 to 3500 nm.

 

Emmission Spectrophotometer:

Fluoromax-4 equipped with an injection port, stirrer, and temperature control.

 

High Resolution NMR Spectrometers:

The EMNS laboratory has access, via the CIREM, to three High Resolution NMR spectrometers (600, 400 and 300 MHz) equipped with different probes for solution studies.

WHAT WE DO

 

  • Spectroscopic analysis of liquid or solid samples by UV-Vis-NIR spectroscopy.
  • Thermal analysis of small-volume liquid samples by nano-DSC.
  • ITC studies of intermolecular interactions.
  • Characterization of colloidal (micelles and liposomes) supramolecular systems (NMR, nano-DSC).

Webmaster: MVG - Last update: June 2017