RESEARCH >> Theme: Supramolecular micellar systems

Webmaster: MVG - Last update: June 2017

SUPRAMOLECULAR MICELLAR SYSTEMS

 

The development of micelles based supramolecular systems for molecular recognition or catalysis in water is an other of our research interest. We are currently focused on the following projects:

#1 Development of micellar nanocatalysts for biomass conversion in water

 

There is currently great interest for the development of environmental-friendly synthetic processes and, in this context, the replacement of commonly-used volatile organic solvents by water is of prime interest. Water is a solvent with little environmental impact but its use has been limited because organic substrates and catalysts are often poorly soluble in water. Micellar systems represent one of the simplest methods to transfer organic catalysis into an aqueous environment. In collaboration with the University of Padova, we are investigating the potential of vanadium-based catalysts in micellar media for the depolymerisation of lignin units. The conversion of model substrates is monitored by NMR and HPLC in order to identify the key parameters controlling the conversion yield in these heterogenous systems. This project is undertaken in the framework of the COST FP1306  Action «Valorisation of lignocellulosic biomass».

 

 

Head: Prof. Kristin Bartik

Co-workers/researchers: Ir William Denis

Collaborations: Prof. Giulia Licini (University of Padova),
Prof. Sabine Van Doorslaer (U. Antwerpen)

Funding: COST, Fondazione Cassa di Risparmio di Padova e Rovigo
PhD fellowship

Publication:

Paramagnetic Relaxation Enhancement Experiments: A Valuable Tool for the Characterization of Micellar Nanodevices

Keymeulen F., De Bernardin P., Dalla Cort A. and Bartik K., J. Phys. Chem. B 117(39), 11654-11659 (2013).

 

 

#2 Elaboration of molecular nanodevices for analyte recognition in water

 

This project, initiated in the framework of the COST CM1005 Action « Supramolecular chemistry in water » co-headed by Prof. Bartik, focuses on the development of novel assays that can be used for the efficient detection of analytes in an aqueous environment. The approach pursued is rooted in supramolecular chemistry and consists in the encapsulation of molecular receptors in micelles in order to take advantage of the numerous properties of these supramolecular assemblies: cooperativity of many immobilized receptors, compatibility with the aqueous environment, change of a physical property during the binding event. Extensive characterisations of the nanosystems are undertaken by advanced physico-chemical techniques as UV-Vis absorption and emission spectroscopies, microcalorimetry and NMR spectroscopy.

 

 

Head: Prof. Kristin Bartik

Co-workers/researchers: Dr Hennie Valkenier, Dr Lionel Marcelis

Collaborations: Prof. Antonella Dalla Cort (La Sapienza - Roma), Prof. Wim Dehaen (KUL, Molecular Design & Synthesis), Ivan Jabin (ULB, Laboratory of Organic Chemistry)

Funding: COST, FNRS

Publications:

A Selective Calix[6]arenes-based Fluorescent Chemosensor for Phosphatidylcholine Type Lipids

Brunetti E., Moerkerke S., Wouters J., Bartik K. and Jabin I., Organic and Biomolecular Chemistry 14, 10201-10207 (2016).

Primary Amine Recognition in Water by a Calix[6]aza-cryptand Incorporated in Dodecylphosphocholine Micelles

Brunetti E., Inthasot A., Keymeulen F., Reinaud O., Jabin I. and Bartik K., Organic & Biomolecular Chemistry 13, 2931-2938 (2015).

Fluoride Binding in Water with the Use of Micellar Nanodevices Based on Salophen Complexes

Keymeulen F., De Bernardin P., Giannicchi I., Galantini L., Bartik K. and Dalla Cort A., Organic & Biomolecular Chemistry 13, 2437-2443 (2015).

Paramagnetic Relaxation Enhancement Experiments: A Valuable Tool for the Characterization of Micellar Nanodevices

Keymeulen F., De Bernardin P., Dalla Cort A. and Bartik K., J. Phys. Chem. B 117(39), 11654-11659 (2013).

Fluoride Binding in Water: A New Environment for a Known Receptor

Cametti M., Dalla Cort A. & Bartik K., Chem.Phys.Chem. 9, 2168-2171 (2008).

 

 

Webmaster: MVG - Last update: June 2017