ION TRANSPORT ACROSS
Synthetic ion transporters are seen as potential therapeutic agents able to restore malfunctions in the natural anion transport across biological membranes by proteins. Our work focuses on the physico-chemical characterization of transmembrane ion transport by organic carriers, with a focus on chloride transport.
Organic molecular receptors and catalysts are rarely water soluble. Micellar encapsulation is a elegant approach to render these systems "water-compatible", by-passing complex synthetic modifications and furthermore providing a protective environment to the receptor/catalyst.
Nano-bioconjugates combine the exceptional properties of nanomaterials, such as the LSPR band of gold and silver nanostructures, with those of biological macromolecules. They are valuable tools which can lead to sensors with extreme selectivity and sensitivity or to smart Drug Delivery Systems and theranostic agents.
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